Everything about Thioglycolic Acid totally explained
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Thioglycolic acid (TGA) is the
organic compound HSCH
2CO
2H. It contains both a
thiol (
mercaptan) and a
carboxylic acid. It is a clear liquid with a strong unpleasant odor. It is readily oxidized by air to the corresponding
disulfide [SCH
2CO
2H]
2.
TGA was developed in the 1940s for use as a chemical
depilatory and is still used as such, especially in the calcium thioglycolate salt form. TGA is the precursor to
ammonium thioglycolate that's used for
permanents. TGA and its derivatives break the
disulfide bonds in the cortex of hair. One reforms these broken bond in giving hair a "perm." Alternatively and more commonly, the process leads to
depilation as is done commonly in
leather processing
TGA is also used in the making of
polyvinyl chloride.
TGA, usually as its dianion, forms
complexes with metal ions. Such complexes have been used for the detection of
iron,
molybdenum,
silver, and
tin.
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